心跳诱发电位提取方法综述:EEG 与 MEG 研究的参数异质性与可重复性挑战
Review of methods to derive the heartbeat-evoked potential: past practices and future directions
一篇发表于 Social Cognitive and Affective Neuroscience 的综述系统评估了心跳诱发电位(HEP)的现有分析流程,指出 EEG 与 MEG 研究中 HEP 提取方法存在明显异质性。
范围综述梳理 199 篇脑电与 8 篇脑磁研究,逐项比对心搏诱发电位的提取窗口、滤波、基线校正与心电场伪迹去除参数。
The heartbeat-evoked potential (HEP) is an implicit, electrophysiological marker of cortical heartbeat processing and interoception, with increasing clinical relevance. However, on the scalp, HEP are low-amplitude signals mixed with cardiac field artefacts (CFA), requiring signal processing pipelines to separate HEP from CFA. This review evaluates current analytical approaches and addresses methodological gaps in HEP pipelines. A scoping review of the literature was conducted focusing on previously published HEP studies. This was to extract HEP processing methods and parameters used in EEG (199 included papers) and MEG (8 included papers). Parameters investigated included the HEP window, filters, baseline correction window, epoch timeframes, minimum RR intervals, epoch amplitude rejection threshold, and CFA removal. EEG and MEG studies revealed clear heterogeneity and variability in the methods used to derive HEP. These clear inconsistencies in HEP parameter use and reporting would appear to challenge the level replicability between studies. In order to ensure reproducibility and transparency, publications should report critical values for reliable HEP extraction, emphasizing the need for standardized methods to enhance study comparability and reproducibility.
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来源:Social Cognitive and Affective Neuroscience · academic.oup.com