自然连续经历记忆在习得后的重激活
Post-Learning Reactivation of Memories for Naturalistic Continuous Experiences
记忆并非对过去的静态记录；相反，回忆这一行为本身可以改变一个事件被回想的方式。有趣的是，多项研究还提示，记忆可能在休息期间被重新激活。然而，重新激活的研究主要针对空间任务和离散刺激，我们对于长时间尺度的自然istic事件是否会发生自发重新激活，以及重新激活如何影响保持，知之甚少。利用fMRI，我们显示，在叙事事件编码期间，海马和默认模式网络中的神经活动模式在休息期间被自发重新激活。与预测相反，重新激活并未增强对电影细节的回忆，而探索性分析反而提示，海马中的重新激活与一周后更偏向要点式的回忆相关。这些发现支持了复杂事件的记忆可能被自发重新激活的观点，但它们提示，重新激活或许并非只是增强情景记忆，而是可能帮助将其转化。
把自发重激活从空间任务和离散刺激扩展到长时程自然叙事事件，并提示海马重激活可能与一周后更偏要点的回忆有关。
Memories are not static records of the past; rather, the act of remembering can change how an event is recalled. Intriguingly, several studies also suggest that memories may be reactivated during rest. However, reactivation has largely been studied for spatial tasks and discrete stimuli, and we know little about whether spontaneous reactivation occurs for long timescale naturalistic events and how reactivation affects retention. Using fMRI, we show that neural activity patterns in the hippocampus and the Default Mode Network during encoding of narrative events were spontaneously reactivated during rest. Contrary to predictions, reactivation did not strengthen recall of movie details, and instead exploratory analyses suggested that reactivation in the hippocampus was associated with more gist-like recall one week later. These findings support the idea that memories for complex events may be spontaneously reactivated, but they suggest that rather than simply strengthening episodic memories, reactivation might help transform them.
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来源：bioRxiv · Neuroscience · biorxiv.org