Trends in Neurosciences· Miao Li, Guang Yang·· 14 天前AI 评分52
Trends in Neurosciences 述评：一条连接睡眠缺失与疼痛的脑环路
A brain circuit linking sleep loss to pain
AI 导读
Trends in Neurosciences 刊出的一篇述评指出，Huang、Wang、Jiao 等人在近期研究中识别出一条连接压后皮层、前扣带皮层与未定带的通路，该通路参与雄性小鼠睡眠剥夺后对机械刺激和热刺激的敏感性升高。依据摘要，睡眠缺失会提高痛觉敏感性，但所涉脑环路此前并不清楚。上述结果为睡眠与疼痛交互的环路机制提供了动物层面的线索，是否适用于人类及其他性别仍需进一步研究。
摘要
Sleep loss heightens pain sensitivity, but the brain circuits involved remain unclear. In a recent study, Huang, Wang, Jiao, and colleagues identified a pathway connecting the retrosplenial cortex, anterior cingulate cortex, and zona incerta that contributes to heightened sensitivity to mechanical stimulation and heat after sleep deprivation in male mice.
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来源：Trends in Neurosciences · cell.com