Neuron· Rachel A. Essner, Kiersten Ruda, Hannah J. Choh, Hakan Kucukdereli, Oren Amsalem, Julia Edelhaus, Gracesenia Chahyadinata, Sverre Grødem, Kristian K. Lensjø, Teresa E. Lever, Mark L. Andermann·· 2026-09-17AI 评分60
Neuron：小鼠脑干臂旁外侧核分区编码进食中的多种身体信号
Brainstem sensing of multiple body signals during food consumption
AI 导读
依据期刊摘要，Essner、Ruda 等人在清醒与麻醉小鼠中开展大规模、多日钙成像，刻画脑干臂旁外侧核神经元如何编码身体信号。结果显示，这一内感受枢纽中空间组织上大体分离的神经元群，分别优先响应口腔或摄入后的进食信号、运动、觉醒状态和/或来自皮层的反馈。该工作提示脑干对进食相关内感受信息存在功能分区，但材料仅提供摘要，未报告样本量、效应量与统计细节，结论仍需全文验证。
摘要
Essner, Ruda, and colleagues use large-scale, multi-day calcium imaging in awake and anesthetized mice to characterize how brainstem lateral parabrachial neurons encode body signals. Largely distinct, spatially organized groups of neurons in this interoceptive hub preferentially respond to oral or post-ingestive feeding signals, locomotion, arousal, and/or feedback from cortex.
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来源：Neuron · cell.com